HISTOPATHOLOGICAL AND HISTOCHEMICAL CHANGES IN VARIOUS TYPES OF MUSCULAR DYSTROPHY
نویسندگان
چکیده
منابع مشابه
Cardiorespiratory changes in progressive muscular dystrophy.
Incipient cardiac failure was detected in 56 per cent of cases of pseudohypertrophic muscular dystrophy, 50per cent oflimb girdle type ofmyopathies, and2 of the 3 cases with 'unclassifled' variety. 'Myopathic pattern' in the electrocardiogram was seen in 82 per cent of the cases of pseudohypertrophic muscular dystrophy who showed abnormal haemodynamics. This suggests that this pattern is due to...
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Duchenne muscular dystrophy (BMD) is an inherited X-link disease. The incidence of this muscle-wasting disease is 1:5000 male live births. Mutation in the gene coding for dystrophin is the main cause of BMD. Most cases of this disease succumb to respiratory and cardiac failure in 3rd to 4th decades. The slow progression of BMD and recent achievement of gene therapies make it as an appropriate c...
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BACKGROUND Differentiation among types of muscular dystrophy (MD) has remained challenging. In this retrospective study, we sought to develop a methodology for differentiation of MD types using analysis of serum enzyme profiles. METHODS The serum levels of enzymes from 232 patients, including 120 with DMD, 36 with BMD, 36 with FSHD, 46 with LGMD, and 11 with EDMD, were evaluated. RESULTS Th...
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An 8-year-old male Japanese Shiba exhibited muscle wasting and a stiff gait. A low-amplitude myotonic discharge was recorded by needle electromyography (EMG). A histopathological examination on a tru-cut biopsy sample from the muscle revealed myofiber size variations. Internal nuclei and cytoplasmic vacuoles were observed in many fibers. A type 1 fiber predominance and many hybrid type fibers w...
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ژورنال
عنوان ژورنال: ACTA HISTOCHEMICA ET CYTOCHEMICA
سال: 1970
ISSN: 0044-5991,1347-5800
DOI: 10.1267/ahc.3.52